Electrochemical Sensing and Biosensing Applications of Laser-Scribed Graphene Electrodes

Khaled Nabil Salama

Sensors Lab, Advanced Membranes and Porous Materials Center, Computer,  Electrical and Mathematical Science and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia


Electrodes are integral part of electrochemical sensors and biosensors, a variety of electrodes have been invented from the emergence of electroanalysis, ranging from hanging mercury electrode, ion-selective electrode, metal electrodes, graphite electrodes, carbon electrodes, screen-printed carbon electrodes (SPCEs), and the most recent laser-scribed graphene electrodes (LSGEs). The significant property that makes LSGE different from other electrodes is its 3D porous architecture of graphene retaining 2D properties of graphene. LSGEs are gaining enormous research interest in diagnostics, especially for point-of-care (PoC) applications. The LSGE production is straightforward via direct laser writing on a polyimide sheet. It provides many advantages such as cost-effectiveness, fast electron mobility, mask-free, green synthesis, good electrical conductivity, porosity, flexibility, mechanical stability, and large surface area. The surface can be further functionalized with functional nanomaterials such as metal nanoparticles, polymers, and metal oxides. In Sensors group, KASUT, we are continuously working on developing biosensing applications of LSGEs for a wide range of healthcare, food safety and water analysis applications. In this session, I will talk about our research on LSGEs, specifically to the biomarkers of cardiovascular disease and cancer biomarkers. As the clinical diagnostics are transforming from traditional lab-centered analysis to PoC settings, the LSGE biosensors hold significant promise in the future disease diagnostics.